Insulin is discovered by Canadian physiologist Frederick Banting and J J R Macleod 

Over 1,500 people dies when the passenger liner Titanic sank after colliding with an iceberg on its first voyage 

Walter Johnson pitches a record tying 4 strike outs in an inning 

Mien Wenneker, Dutch prince Henrys lover, weds Uncle Cornelis Abbo 

New York Giants Red Ames 2nd no-hitter, loses in 13 on a 7 hitter to Dodgers 

First British motorized burial 

An early 50 mile race is won by an electric car in over 2 hrs 

International Exposition opens in Paris 

US inventor Thomas Edison gave a public demonstration of his kinetoscope, a moving-picture machine